Patients with zoonotic ORFV infection develop nodular and papillomatous lesions mainly on the hands, face, and mouth. Contagious ecthyma (contagious pustular dermatitis) is a highly contagious disease that primarily affects sheep, goats, and wild ruminants, and is characterized by the formation of papules, nodules, or vesicles that develop into thick crusts or heavy scabs on the lips, gingiva, and tongue. The major viral envelope protein B2L and virus interferon resistance (VIR) genes have been used to measure genetic variation among parapoxvirus since these genes are a highly conserved. This group includes the orf virus (ORFV), pseudocowpox virus, and bovine papular stomatitis virus that infect cattle along with the parapoxvirus of red deer in New Zealand. Members of the genus Parapoxvirus from the Poxviridae family are oval, enveloped viruses containing a double strand (ds)DNA genome.
goat isolation orf virus phylogenetic analysis This result indicates that the orf viruses might have been introduced from dairy goats into the Korean black goat population. Phylogenetic analyses revealed that orf viruses from Korean black goats were most closely related to an isolate (ORF/09/Korea) from dairy goats in Korea.
Sequences of the major envelope protein and orf virus interferon resistance genes were determined and compared with published reference sequences. One orf virus (ORF/2011) was isolated from an ovine testis cell line (OA3.Ts) for use as a vaccine candidate. 2013 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.įive cases of orf virus infection in Korean black goats were diagnosed in our laboratory between 20. J Vet Sci JVS Journal of Veterinary Science 1229-845X 1976-555X The Korean Society of Veterinary Science 10.4142/jvs.2013.14.2.227 Short Communication Isolation and characterization of orf viruses from Korean black goats Oem Jae-Ku Chung Joon-Yee Kim Yong-Joo Lee Kyoung-Ki Kim Seong-Hee Jung Byeong-Yeal Hyun Bang-Hun Animal Disease Diagnostic Division, Animal and Plant Quarantine Agency, Anyang 430-824, Korea.Ĭorresponding author: Tel: +82-3 Fax: +82-3 06 2013 21 06 2013 14 2 227 230 03 09 2012 25 10 2012 15 12 2012 © 2013 The Korean Society of Veterinary Science. Warning: getimagesize(/home/virtual/kamje/synapse/upload/SynapseXML/0118jvs/thumb/.jpg): failed to open stream: No such file or directory in /home/virtual/kamje/synapse/articles/Figure.php on line 138
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